Scientists are closing in on a deceptively simple idea with radical implications: that a single protein signal in the blood can push aging immune cells to behave as if they were young again. Instead ...

Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refinin ...

The incidence of lethal prostate cancer (PCa) is disproportionately higher in African American (AA) men compared to Caucasian (Cau) men. Racial differences in lipid reprogramming have been implicated ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

Mitochondrial transfer is known to occur from the tumor microenvironment into cancer cells, but now, Swiss researchers have shown a possible precursor to this is that cancer cells smuggle their ...

ABSTRACT: Epigenetics can be defined as a heritable or reversible change in gene expression that is not accompanied by changes in DNA sequences. Epigenetics provides an additional layer of ...

Scientists from Nagoya University have developed a fast and safe method to create lung cells from skin-like fibroblasts – without using stem cells. This technique could allow for new regenerative ...