Scientists from Brigham and Women's Hospital, speaking at the American College of Rheumatology/Association of Rheumatology Health Professionals annual conference in ...

A newly developed tool to analyze the cellular and molecular profiles of synovial tissue and peripheral blood may help unlock clues about rheumatoid arthritis and lead to better therapies, according ...

SAN DIEGO - A newly developed tool to analyze the cellular and molecular profiles of synovial tissue and peripheral blood may help unlock clues about rheumatoid arthritis and lead to better therapies, ...

Advances in single-cell sequencing technology have significantly improved our understanding of health and disease. One of the first and most critical steps in this process is tissue dissociation, ...

Adoptive cell transfer, in which a patient’s own immune defenses are boosted or rewired to kill cancer cells, is one of the most effective forms of personalized cancer care to ever reach patients.

Tumour-infiltrating lymphocyte (TIL) therapy is showing great promise in the treatment of patients with advanced malignant melanoma. However, the translation of TIL therapy to non-melanoma tumours ...

Surgical implantation of tumour pieces has been used regularly in the passage of tumour models. This involves an invasive surgical procedure, carried out under anaesthesia; ensuring mice have adequate ...

Cell suspensions can readily be prepared from monolayers of cultured cells, e.g. human umbilical vein endothelial cells (HUVECs) by the dissociation procedures used when passaging cells (see below).