Many of the food industry’s most persistent problems exist not in the realm of business and economics – scaling, costs of materials and the like – but in nature itself. Crops, which the food industry ...
A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...
Proteins are biology’s molecular machines. They’re our bodies’ construction workers—making muscle, bone, and brain; regulators—keeping systems in check; and local internet—responsible for the ...
Adam Broerman, a graduate student in the University of Washington’s Institute for Protein Design, studies an engineered protein that can turn off protein interactions. (IPD Photo / Ian Haydon) The ...
Proteins designed by artificial intelligence (AI) are being considered for use in treating everything from snakebites to cancer. A Nature Communications paper, out this week, describes how Australian ...
Biophysicists have elucidated why unexpected structures can sometimes arise during protein design. Artificially designed proteins are usually based on building blocks that obey strict rules of ...
Where is DeepMind’s AI protein design spinout? The Alphabet-owned AI company took the biology world by storm in 2020 with AlphaFold2, the protein structure prediction AI platform that “solved” a ...
A protein engineered by University of Washington scientists wraps around its target. (Institute for Protein Design Image) The wiggly targets known to scientists as “intrinsically disordered proteins” ...
Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing question: Could a single molecule switch between two different roles like a ...