Figure 1: Diverging the decoding properties of natural and orthogonal ribosomes. To demonstrate that ribo-X synthesizes proteins with a fidelity comparable to the natural ribosome, we compared the ...

Honolulu, Hawaii--(Newsfile Corp. - August 12, 2025) - Orthogonal Thinker, Inc. ("Orthogonal") today announced it has entered into a definitive plan to acquire and consolidate Ei.Ventures, Inc. ("EI") ...

The central dogma processes of DNA replication, transcription, and translation are responsible for the maintenance and expression of every gene in an organism. An orthogonal central dogma may insulate ...

From RNA interference (RNAi) to CRISPR, there are several methods that researchers can use to manipulate gene function, each with its own strengths and weaknesses. Orthogonal validation – the ...

Simply put, orthogonal validation uses additional methods that provide very different selectivity to the primary method to confirm or refute a finding. All methods are independent approaches that can ...

One of the fundamental purposes of biotherapeutic research, development, and production is to assure the safety and efficacy of medicinal products in clinical settings. Analytical tools are critical ...

There is evidence that the orthogonal grid plan, which is one of the most common types of urban planning today, dates back to antiquity. Streets intersect at right angles to each other, resulting in a ...

Discordance between plasma and tumor variant calling has been attributed primarily to tumor heterogeneity, whereas technical variables remain largely unexplored. Our orthogonal approach identified ...

Orthogonal frequency-division multiple-access provides Wi-Fi 6 with high throughput and more network efficiency by letting multiple clients connect to a single access point simultaneously. Wi-Fi 6, ...