Welcome to Lab Dish, a First Opinion column on regenerative medicine from Paul Knoepfler. Twenty years ago, the use of human embryonic stem cells in research was among the most fiercely debated topics ...

An unprecedented international effort to decode how cells manage the transport of chemical substances has culminated in four studies published in Molecular Systems Biology. Led by Giulio Superti-Furga ...

Thanks to increasingly efficient and affordable gene sequencing technologies, we can now chart our genetic blueprint in unprecedented detail. But what does each gene do? Of the roughly 20,000 genes ...

The first phase of the U.K. synthetic human genome project has successfully completed, realizing key steps in chromosome synthesis. The work has demonstrated a multistep method for transfecting mouse ...

Established in 2016, the Human Cell Atlas (HCA) consortium set out to create a comprehensive biological map of cells within the human body. Now progressing into a data integration phase, the HCA is ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...