Cornell University researchers have identified a calcium-sensitive structural “gate” inside a bacterial enzyme that toggles ...

Cornell researchers have uncovered a built-in molecular "gate" that controls the production of the molecule nitric oxide, a crucial signaling molecule throughout biology that in humans helps regulate ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Researchers at the University of Virginia School of Medicine have identified a specific enzyme inside immune cells that keeps Toxoplasma gondii, one of the most common brain parasites on the planet, ...

Primary immunodeficiencies are genetic disorders that impact on the immune system due to defective function of a variety of genes. Among those molecules are ...

Mitochondrial defects are associated with the development of diseases such as type 2 diabetes (T2D). Studies in mice and in human tissues, by researchers at the University of Michigan, have now found ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...